BXMAS1 |
BYE1 |
ILT10 |
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Anumanthan et al (1998) have cloned the cDNA encoding this protein identified by a monoclonal antibody of the same name (Maïza et al, 1993). BY55 is a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids that most likely exists as disulfide-linked multimers.
BY55 is expressed on the CD56(dim), CD16(+) subset of NK-cells, which have high cytolytic activity. It is not expressed or induced on CD56(bright), CD16(-) NK-cells, a subset with high proliferative, but low cytolytic, capacity. In human tissues, BY55 mRNA is expressed only in spleen, peripheral blood lymphocytes, and gut lymphocytes
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