CDIP1 |
CDIR |
Dermaseptin S7 |
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[chemokine-derived inhibitory peptide-2] This synthetic peptide of 19 amino acids (KISLQRLKSYVITTSRCPQ) is derived from the CC-Chemokine CCL13 and corresponds to CCL13(19-37) of the mature chemokine (Mendez-Enriquez E et al, 2008). CDIP-2 shows anti-inflammatory activities and displays antagonist functions in in vitro chemotaxis assays using monocytic cell lines. CDIP-2 significantly reduces peribronchial, perivascular infiltrate and mucus overproduction in an ovalbumin-induced allergic lung inflammation murine model.
Méndez-Enríquez et al (2014) have reported that the anti-inflammatory
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