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These cell clusters represent a population of cells are generated in the human adrenal cortex during remodeling with age (Hadjidemetriou et al, 2019).. The cells are relatively undifferentiated and secrete DLK1 [delta like non-canonical Notch ligand 1]. The function of these cell clusters is not known but the authors have suggested that they might play a role in the pathogenesis of adrenocortical carcinoma in humans.
For related information of interest see also: Cell types Dictionary, Cell lines in Cytokine Research, Cell culture.
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