DMPK binding protein |
Dms |
Opiscorpine-2 |
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DMQD-CHO (the aldehyde derivative of the tetrapeptide Asp-Met-Gln-Asp) or Ac-DMQD-CHO (the N-acetylated form) is a selective inhibitor of one of the caspases, caspase-3 (Hirata et al, 1998).
General note on chemical modifications: Practically all of the available inhibitors of caspases, be they specific or pan-caspase inhibitors, come in chemically modified form. The introduction of an aldehyde group at the C-terminus of the short peptide sequences recognized by caspases
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