ERRFI1 |
ERT |
IDB3 |
||
[EGFR-related protein; EGF receptor-related protein] The cDNA encoding ERRP has been isolated from the rat gastroduodenal mucosa (Yu et al, 2001). The encoded protein (479 amino acids) shows approximately 85 % homology to the external domain of the rat EGF receptor.
ERRP is present in most, if not all, normal human epithelial cells. Overexpression of ERRP in the colon cancer cell line, HCT116, markedly reduces proliferation in monolayers and colony formation in soft agar (see also: colony formation assay). In another colon cancer cell line
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |