IPAF |
IPA-S4/5 cells |
ATG4A |
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[IPAF inflammasomes]
The IPAF inflammasome is also being referred to as the NLRC4 inflammasome, which can process the precursor of IL1-beta and/or IL18. It is one of several molecular assemblies known as inflammasome. It is composed of NLRC4 (a member of the NLR family known also as IPAF), the molecular adapter ASC, and caspase-1 (Mariathasan et al, 2004). IPAF functions as an intracellular pattern recognition receptors or pathogen recognition receptor (Miao and Warren, 2010).
For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also:
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