NCK interacting protein with SH3 domain |
NCL |
metalloproteinase-like disintegrin-like cysteine-rich protein-2-beta |
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(approved gene symbol) [NCK interacting protein with SH3 domain]. The name of this protein is derived from its ability to interact with a multifunctional adaptor protein, NCK [NCK adaptor protein]. The protein has been described independently as murine WISH [WASP-interacting SH3 protein] (N-WASP-binding protein) by Fukuoka et al (2001) who reported its involvement in the activation of actin polymerisation..
NCKIPSD has been identified independently as AF3p21 [ALL1-fused gene from chromosome 3p21], a fusion partner of the MLL [myeloid/lymphoid leukemia gene; mixed lineage leukemia
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