NEDF |
NEFA |
EGP40 |
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[neurite extension factor] NEF is a disulfide-bonded dimer of a protein related closely to S100 (S100-beta). NEF induces process outgrowth from chick embryo cerebral cortical neurons. It also induces rapid morphological differentiation of Neuro-2A murine neuroblastoma cells, leading to the formation of elaborate multipolar neurites (Kligman and Shieh, 1987). See also: S100b(2-11) for a fragment.
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