NEGF-1 |
neglect-induced death |
cone rod dystrophy 5 |
||
[neurite growth-promoting factor-2] The human NEGF-2 gene maps to chromosome 11p13-p11. The mature protein has a length of 121 amino acids and is 46 % homologous with another heparin binding neurite outgrowth-promoting factor, NEGF-1 (see: HBNF, heparin binding neurite-promoting factor). NEGF-2 is known also as midkine.
The protein also possesses neurite outgrowth-promoting activity and the gene is a member of a highly conserved, developmentally regulated human gene family. NEGF-2 plays a role in nervous system development and/or maintenance and its expression is developmentally regulated. NEGF-2 protein is barely detectable before and after approximately one half to two thirds of the gestation period.
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |