pancreozymin |
Pandinin-1 |
KESVRLCGLEYIRTVIYICASSRW |
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[pancreatic derived factor] PANDER is identical with a member of a cytokine-like gene family, FAM3B [family with sequence similarity 3 member B] (approved gene symbol) and has been termed also 2-21 and C21orf11 [chromosome 21 open reading frame 11], identified in a database search for novel four-helix-bundle cytokines. The gene has been identified independently as PRED44.
PANDER is expressed at high levels in the islets of Langerhans of the endocrine pancreas. It is produced by pancreatic A-cells and beta-cells (Yang et al, 2005).
Role in apoptosis
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