PARC |
Pardaxin |
calcitonin cells |
||
[Pro-apoptotic protein required for cell survival] The approved gene symbol for this protein is GPN3 [GPN-loop GTPase 3]. A previous designation is ATPBD1C [ATP binding domain 1 family member C].
This protein has been identified by Sanchez-Olea et al (2008). PARCS is involved in both cell cycle progression and cell death by apoptosis. PARCS interacts with APAF-1. The activation of caspase-9 and caspase-3 mediated by APAF-1 is decreased in HeLa cells with reduced PARCS expression. PARCS deficiency blocks cell proliferation in non-tumorigenic cells
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |