PB1 |
PB1 domain |
T-lymphocyte-expressed seven-transmembrane domain receptor |
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a pre-B-cell line established from murine bone marrow (Mire-Sluis et al, 2000). The cells are dependent on IL7 (see also: factor-dependent cell line) and have been used to establish a bioassay for human and murine IL7.
The IL7 bioassay is reported to be reproducible and to be able to reliably detect 50 pg/mL IL7. It is suitable for use with plasma and serum samples. The assay is completely unresponsive to any other stimulatory cytokines tested and is not affected by a wide variety of inhibitory cytokines. High levels of IFN-alpha
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