PL |
PL-A |
Dies1 |
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This protein has been identified by Morrish et al (2001). It is expressed in the placenta (human syncytiotrophoblasts and extravillous cytotrophoblasts) and is involved in trophoblast development. The protein is a member of the TGF-beta family of cytokines. It is identical with GDF15 [growth/differentiation factor-15] and MIC1 (macrophage inhibitory cytokine-1), which have been identified independently as PDF (prostate-derived factor), PLAB (Placental bone morphogenetic protein), PTGF-beta, and NAG-1 [NSAID activated gene-1].
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