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ADNP

(approved gene symbol) [activity-dependent neuroprotective protein, activity-dependent neuroprotector; activity-dependent neuroprotector homeobox protein] Another designation is ADNP1 [activity-dependent neuroprotective protein 1]. The cDNA encoding ADNP has been identified independently as KIAA0784.

This protein of 828 amino acids has been identified as a mediator of neuronal survival induced by various stimuli causing cell death by apoptosis. Expression of ADNP is upregulated in astrocytes by VIP. ADNP is widely distributed in the mouse hippocampus, cerebellum, and cerebral cortex (Gozes et al, 2000). ADNP is expressed mainly in ... ... ... ... ... Subscribe to continue reading! ... ...

 

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