AEDGDAKTDQAEKAEGAGDAK |
AEEGIAAGGVMDVNTALQEVLKTZ |
GZMH |
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This peptide, termed SP6024 by the authors, has been identified by bioinformatics analysis. The sequence is derived from a caspase-10 and has been shown to be a potent inducer of endothelial cell apoptosis in the presence of bFGF and VEGF, causing the release of caspase-3 and caspase-7 (Koshimaki et al, 2012).
For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia.
See also: Angiogenesis Dictionary section of this encyclopedia for other entries directly bearing on factors and processes involved in the generation of new
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