AGM region |
AGM-S3-A7 |
water-soluble tetrazolium |
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This stromal cell line was derived from the aorta-gonad-mesonephros region of a 10.5 days postcoitum mouse embryo. This is the region in which definitive hematopoietic cells first appear during mammalian embryonic development (see also: hematopoiesis). The cells express CD13, vascular cellular adhesion molecule 1, and Sca-1. RT-PCR quantitation of cytokines reveals the presence of mRNA for SCF, IL6, and Oncostatin M. Expression of IL3, IL11, LIF, G-CSF, GM-CSF, thrombopoietin, and
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