AILE25 |
AIM |
RP105 |
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[Activation-inducible lymphocyte immunomediatory molecule] AILIM is a lymphocyte adhesion molecule of 47 kDa expressed constitutively on thymocytes. Expression, which is low in T-cells, is induced on naive T-cells after cell activation. Its expression is induced by the treatment with PMA plus Calcium ionophore or the engagement of CD3 (Tezuka et al, 2000). The major population of AILIM positive cells in rat splenocyte is CD45RA(+) B-cells (Tezuka et al, 2000).
The protein is the rat homolog of ICOS
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