ALDH6A1 |
ALDIYSAVDDASHEKELP |
acinar pancreatic cells |
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(approved gene symbol) [Aldehyde dehydrogenase family 18 member A1] The enzyme is known also as PYCS [1-pyrroline-5-carboxylate synthase, pyrroline-5-carboxylate synthetase], P5CS [Delta-1-pyrroline-5-carboxylate synthase], and GSAS [glutamate-gamma-semialdehyde synthetase].
This enzymeconverts glutamate to glutamate 5-semialdehyde and catalyzes the first two steps of the de novo biosynthesis of proline, ornithine, and arginine (Hu et al, 1999; Basumgartner et al, 2000). The human cDNA has been cloned by Aral et al (1996). Hu
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