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[apoptosis inhibitor 2-MALT1 fusion protein] An oncogenic fusion protein consisting of API2 [Apoptosis inhibitor 2] (BIRC3 or cIAP2) (hence also cIAP2-MALT1, BIRC3-MALT1, MALT1-API2) and a member of the proteases known as paracaspases, MALT1 [MALT lymphoma-associated translocation 1]. The fusion protein is generated by a specific chromosomal translocation in a high percentage of mucosa-associated lymphoid tissue (MALT) lymphomas. See: Paracaspase-1.
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