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APR2

[Apoptosis-related protein-2] The gene encoding this protein has been identified by Hassan et al (2005). In databanks the protein is listed as FAM215A [family with sequence similarity 215 member A] and C17orf88 [chromosome 17 open reading frame 88].

Inhibition of gene expression by means of antisense RNA induces resistance to cell death involving FAS in various cells lines (HepG2 (hepatocellular carcinoma cells), A375 (melanoma cells), CLS-354 (squamous carcinoma cells)). APR2 is crucial also during all-trans-retinoic acid-induced ... ... ... ... ... Subscribe to continue reading! ... ...

 

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