AT744 |
ATAP |
fibroblastoid synovial cells |
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[activation induced T-cell derived and chemokine related] A cDNA clone isolated from a collection of human T-cell activation genes (see also: cell activation) (Müller et al, 1995). ATAC mRNA is expressed exclusively in activated CD8(+) T-cells approximately 30 minutes after stimulation of cells by phorbol 12-myristate 13-acetate (see: Phorbol esters) and the Calcium ionophore A23187, which are both required for expression. Cyclosporin A (see: CsA) blocks induction completely.
ATAC mRNA encodes a protein of 114 amino acids (12.52 kDa), giving rise to a mature secreted protein
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