Angiopeptin |
Angiopoietin-2 |
4-alpha-hydroxy-tetrahydropterin dehydratase |
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abbr. Ang-1, ANGPT1. This factor was found in the conditioned medium of the human neuroepithelioma cell line SHEP1 and the mouse myoblast cell line C2C12ras. The cDNA encoding a protein of 498 amino acids was isolated by using a secretion-trap expression cloning procedure exploiting the presence of a signal sequence present in growth factors that are secreted by producer cells (Davis et al, 1996). Murine and human factors show 97 % identity at the amino acid level. The cDNA encoding angiopoietin-1 has been identified independently as
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