Antiproliferative protein |
Antisense |
T2P |
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[Antiregulatory T-cell]
abbr. Anti-Tregs. This term refers to a population of self-reactive immune-suppressive T-cells that specifically recognize human HLA–restricted epitopes derived from proteins highly expressed in professional antigen-presenting cells under various physiological conditions such as inflammation and stress. This cell type has been described in patients with cancer, but antiregulatory T-cells are present also in the natural T-cell repertoire of healthy individuals.
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