Apopain |
Apoprotein E |
PBLs |
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[Apoptosis-targeting Peptide-1] This peptide, CQRPPR, Cys-Gln-Arg-Pro-Pro-Arg, has been identified as a targeting peptide by phage display selection (Wang et al, 2010). ApoPep-1 homes to apoptotic and necrotic cells in tumor tissue, also binds to apoptotic and necrotic cells in culture, and shows only little binding to live cells. was observed. The receptor for ApoPep-1 has been identified as histone H1 that is exposed on the surface of cells undergoing cell death by apoptosis. Thus, the peptide is being referred to as histone H1 targeting peptide. In
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