ASS1 |
ASSLNIA |
death ligand signal enhancer |
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This form of cell death has been observed in the model organism Caenorhabditis elegans (Johnsen and Horvitz, 2016). The initiation of the cell death process in certain cell types requires the core apoptotic pathway (gene CED3), but cell death does not occur unless the cells are engulfed by another cell acting as a phagocyte, requiring genes CED1, CED2. The mechanism of assisted suicide is not clear yet. It is not known whether this kind of cell death also occurs in mammalian cells, but the process is reminiscent of phagoptosis and entosis, which also require engulfment of
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