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Atypically-shaped cardiomyocytes

[Atypically-shaped cardiomyocyte]

This cell type has been identified in ventricles of mouse hearts by Omatsu-Kanbe and Matsuura (2009) as resident heart cells that are distinct from terminally-differentiated cardiomyocytes. The cells are rounded cells when cultured and gradually change their shape and then start self-beating. These self-beating cells are mostly multinucleated, do not appreciably proliferate, and undergo a further morphological maturation process to form highly branched shapes with many projections. The cells exhibit spontaneous action potentials arising from the preceding slow diastolic depolarization. Cells ... ... ... ... ... Subscribe to continue reading! ... ...

 

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