B7S1 |
B7S4 |
DSP |
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[B7 superfamily member 3] This protein is a member of the B7 superfamily of proteins. Whereas humans contain a single-copy gene, mice appear to contain 10 B7S3 relatives.
Two differentially spliced isoforms are expressed in lymphoid and nonlymphoid tissues. The protein acts as a negative regulator of T-cells and can inhibit T-cell proliferation, IL2 production, and reduce production of cytokines by effector T-cells.
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