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BALL-1 induced Eosinophil chemotactic factor

A factor of 10-30 kDa produced by human mononuclear leukocytes (MNL), probably CD4(+) T-cells when they are cocultured with irradiated B-cell lymphoma cells (BALL-1 cell line). This factor suppresses the respiratory burst of eosinophils. The presence of antibodies directed against IL2, IL3, IL5, and GM-CSF fails to suppress the activity of this eosinophil chemotactic factor. ECF appears to be identical with the chemoattractant for eosinophils, Ecalectin (Yoshida et al, 1994).

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