BB18 |
BB-10010 |
KIAA0472 |
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The monoclonal antibody of this name, and an addition antibody, designated BA27, recognize a 140 kDa disulfide-bonded homodimeric polypeptide on a small subset of circulating T-cells and on most T-cells after cell activation in vitro. BB27 identifies CD4(+) CD8(+) cell subsets different from those defined by CD45RA, CD45RO, CD26, CD29, CD31, and CD38. BB27 also subdivides the CD28 subset. A proliferative response to CD28 monoclonal antibodies and phorbol myristate acetate stimulation is obtained exclusively in the CD28(+)
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