BAX-tau |
Bb |
ADAMTS20 |
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[Bay K 8644]
[1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester]; [methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate]
BayK8644 is a dihydropyridine derivative structurally related to the calcium channel antagonist Nifedipine. In contrast to Nifedipine, it functions as a calcium channel agonist. BayK8644 acts as a competitive antagonist of nifedipine in contractility experiments. It increases calcium channel activity by directly interacting with Calcium channels to promote entry of calcium ions (Ochi et al, 1984; Thomas et al, 1985; Schramm et al, 1983). BayK8644 is used primarily as a research tool to study calcium channel activities (Bechem and Schramm, 1987). For its application in the generation of cells with characteristics of
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