bursicon-beta |
Bursopentin |
FKFGSFIKRMWRSKLAKKLRAKGKELLRDYANRVLSPEEEAAAPAPVPA |
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Bursin is a tripeptide (Lys-His-Glyamide; KHGamide) isolated from the bursa of Fabricius, the central humoral immune organ unique to birds which plays important roles in B-lymphocyte differentiation. It was described originally as a B-cell differentiation hormone termed Bursopoietin (Brand et al, 1976).
Bursin selectively stimulates the differentiation of avian and mammalian B-cells from their precursors (Audhya et al, 1986; Lassila et al, 1989).
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