CD29 |
CD30L |
GWRPNSREDSVEAGLPLQVRGYPEE |
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[CD30(+), CD30(-)]
This cell surface antigen is known also as Ki-1, Ki-2, R4-4, or Ber H2 antigen. The approved gene symbol is TNFRSF8 [TNF receptor superfamily member 8] and refers to the homology of CD30 to other members of the TNF receptor superfamily.
The protein is expressed on mitogen-activated B-cells and T-cells, but not on resting lymphocytes or monocytes. CD30 is expressed also on Hodgkin and Sternberg-Reed cells of Hodgkin's lymphomas and on most Hodgkin-derived cell lines. CD30 is expressed also on a subset of non-Hodgkin's lymphomas
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