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CFAP299

(approved gene symbol) [Cilia- and flagella-associated protein 299]. This protein is known also as C4orf22 [chromosome 4 open reading frame 22]. This protein of 233 amino acid residues is highly conserved in metazoan species. It is expressed predominantly in mouse testis, mainly distributed in the cytoplasm of spermatogonia and primary spermatocytes. Over-expression significantly inhibits apoptosis and promotes cell cycle progression with an increase in the cell number of S phase and G2 phase of the cell cycle in germ cell-derived GC-1 cells. Silencing of gene expression in ... ... ... ... ... Subscribe to continue reading! ... ...

 

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