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CK11

[Trout chemokine 11] CK11 is a rainbow trout (Oncorhynchus mykiss) CC-Chemokine phylogenetically related to both mammalian CCL27 and CCL28. CK11 is strongly transcribed in skin and gills and has been shown to be upregulated in response to infection with the rhabdovirus viral hemorrhagic septicemia virus (VHSV) (Montero et al, 2011).

Muñoz-Atienza et al (2019) have reported that CK11 is not chemotactic for unstimulated leukocyte populations from central immune organs or mucosal tissues but instead functionas as a potent antimicrobial peptide active against a wide range of rainbow trout Gram-positive bacteria and Gram-negative bacteria ... ... ... ... ... Subscribe to continue reading! ... ...

 

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