CR4 |
CR8 |
Lymphoma |
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[cytokine response gene 6] Beadling et al (1993) have identified a cDNA encoding CR6 as one of the immediate-early response genes expressed in T-lymphocytes after stimulation with IL2. CR6 is identical with gadd45-gamma. The protein has been identified independently as OIG37 [oncostatin M inducible gene-37], DDIT2 [DNA damage-inducible transcript-2], and GRP17 [gadd-related protein 17 kDa].
Like other gadd45 proteins CR6 suppresses colony formation of human lung carcinoma H1299 cells. Analysis of CR6 expression during the development of
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