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CR6

[cytokine response gene 6] Beadling et al (1993) have identified a cDNA encoding CR6 as one of the immediate-early response genes expressed in T-lymphocytes after stimulation with IL2. CR6 is identical with gadd45-gamma. The protein has been identified independently as OIG37 [oncostatin M inducible gene-37], DDIT2 [DNA damage-inducible transcript-2], and GRP17 [gadd-related protein 17 kDa].

Like other gadd45 proteins CR6 suppresses colony formation of human lung carcinoma H1299 cells. Analysis of CR6 expression during the development of ... ... ... ... ... Subscribe to continue reading! ... ...

 

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