Caspase-14b |
Caspase-16 |
integrin-alpha-D |
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abbr. CASP15. This enzyme is a member of a family of evolutionarily conserved cysteine protease proteins known as caspases. Many of these enzymes are part of a proteolytic cascade that plays a central role in cell death by apoptosis. Eckhart et al (2005) have identified caspase-15 in various mammalian species including pig, dog, and cattle. A homolog of caspase-15 is absent in the human and the mouse genome.
Recombinant porcine caspase-15 has been shown to undergo autocatalytic processing into its subunits and cleaves both tetrapeptide caspase substrates and the
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