childhood-onset Polyarteritis nodosa |
CHILP |
Manchester inhibitor |
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a class of proteins containing regions of similarity to bacterial and fungal chitinases. They do not possess chitinase activity, but bind chitin-like oligosaccharide ligands. Possibly these proteins play a role in innate responses to chitinous pathogens, such as fungi and nematodes. For examples see: CHI3L1, CHI3L2, CHI3L3.
For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.
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