Cn-AMP1 |
cnc-2 |
BCL2-like-13 |
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[Cocos nucifera antimicrobial peptide 2] This peptide with the sequence TESYFVFSVGM is an anionic host defence peptide from green coconut water of the plant Cocos nucifera (Mandal et al, 2009). It shows no sequence homology to other antimicrobial peptides.
Prabhu et al (2014) have reported that the peptide is an anticancer peptide that shows anti-proliferative activity against the 1321N1 and U87MG human glioma cell lines. The long hydrophobic C-terminal sequence (YFVFSVGM) behaves as a cell-penetrating peptide that drives the translocation of Cn-AMP2 across the cancer cell membrane.
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