Cytokeratin-18 M65 |
Cytokine 1 |
O-acetyl ganglioside synthase |
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approved gene symbol: KRT19 [keratin-19]; abbr. often K19, CK19. A databank designation is also K1CS [keratin, type I cytoskeletal 19].
Cytokeratin-19 is a 40 kDa acidic keratin - (hence the designation 40 kDa keratin - found in the transient superficial layer that envelopes the developing epidermis (periderm). Cytokeratin-19 has been shown to be expressed in the early human embryo (Savtchenko et al, 1988). It is expressed often in epithelial cells in culture and in some carcinomas. Cytokeratin-19 is a constituent of the intermediate filament protein responsible for the structural integrity of epithelial cells
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