Cytokine gene transfer

Cytokines are important modulators of host antitumor responses. Antitumor cytokine therapies are currently limited by important systemic and often life-threatening toxicities. With the availability of cloned cytokine genes and Recombinant cytokines and a better, albeit still limited, understanding of tumor/host interactions the tools and concepts of gene therapy are now being applied to the development of effective new cancer treatments. Gene therapy with cytokines will probably be a useful complement to conventional treatments (surgery, chemotherapy, radiotherapy) in the near future and may allow the prophylactic or therapeutical effective vaccination against cancer ... ... ... ...
 
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Entry last modified: November 2002