DDX60L
[DEAD box helicase 60-like; DEAD box polypeptide 60-like] This protein, which contains a DEAD box and may act as a cytoplasmic RNA helicase, has been shown to be produced in response to IFN-gamma and virus infection in primary human hepatocytes. It is related to DDX60.
In human hepatoma cells it appears to act as a restriction factor for hepatitis C virus (Grünvogel et al, 2015). Knock-down of DDX60L expression increased/s HCV replication in Huh-7 hepatoma cells, and rescues HCV replication from type 2 interferon as well as type 1 interferon and type 3 interferon
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