Drosophila scavenger receptor CI
abbr. dSR-CI. Drosophila scavenger receptor CI has been cloned by Pearson et al (1995). The protein, encoded by gene CG4099, contains several well-known sequence motifs, including two complement control protein domains and somatomedin B domains, MAM domains, and mucin-like domains. Expression is restricted to macrophages / hemocytes during embryonic development. When expressed in mammalian cells, Drosophila scavenger receptor CI exhibits high affinity and saturable binding of acetylated low density lipoprotein and mediates its degradation.
Drosophila scavenger receptor CI is a pattern recognition receptor
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