endo-siRNAs |
Endosome-associated ubiquitin isopeptidase |
parathyroid hormone receptor |
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This is a form of autophagy that involves the sequestration of cytosolic proteins into late endosomes / multivesicular bodies. Sequestration can be non-selective or can occur in a selective manner mediated by HSPA8 (HSC70). Endosomal microautophagy differs from chaperone-mediated autophagy because substrate unfolding is not required. Also, the process is independent of the receptor LAMP-2 but requires ESCRT [endosomal sorting complexes required for transport] (ESCRT-I and ESCRT-III) protein machinery (Sahu et al, 2011).
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