Epidermal lymphocyte chemotactic factor |
epidermal pentapeptide |
Beta-Defensin-1 |
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abbr. ELCs. This cell type, described by Almeida et al (2015) has been found in the murine epidermis. The cells resemble peripheral T-cell progenitors which transiently seed the epidermis during late embryogenesis in both wild-type and T-cell-deficient mice. Epidermal Lymphoid Cells expressed Thy1 and CD2, but lack CD3 and TCRαβ/γδ at their surface, reminiscent of the phenotype of extra- or intra- thymic T-cell progenitors. Similar to dendritic epidermal T-cells, Epidermal Lymphoid Cell are radioresistant and capable of self-renewal
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