FGLamide allatostatins |
FGLPMLSILPKALCILLKRKC |
C5a anaphylatoxin chemotactic receptor C5L2 |
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[NCAM FG loop peptide] This peptide, EVYVVAENQQGKSKA, is derived from the fibronectin type 3 repeat module FN3,2 of NCAM [neural cell adhesion molecule] (Kiselyov et al, 2003), corresponding to the binding site of NCAM for the fibroblast growth factor receptor FGFR1. It acts as a FGF mimetic peptide, binding to, and activating FGFR1 and downstream signaling molecules and cascades (Chen Y et al, 2010; Neiiendam et al, 2004).
FGL peptide induces the differentiation of primary neurons
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