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FL5.12

a murine pro-B-cell lymphoid cell line derived from fetal liver that is dependent on IL3 (see also: Factor-dependent cell lines). When FL5.12 cells are deprived of IL3, greater than 90 % of all cells accumulate in the G0 phase of the cell cycle. Upon readdition of IL3, the cells reenter the active phases of the cell cycle.

FL5.12 cells have been used in bioassays of IL3. The cells do not respond to GM-CSF, IL1 and IL6.

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