fission 1 homolog |
FITLLLRKFICSITKKC |
DNA damage-induced apoptosis suppressor |
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[fos-induced transcript-1] This gene has been identified by Superti-Furga et al (1991) as a target gene of the fos proto-oncogene. The rat Fit-1 gene has been characterized by Bergers et al (1994), who have shown that two isoforms encoded either secreted or membrane-bound forms of the protein. Sequence analysis demonstrates that the encoded protein is identical with T1/ST2 (ST2), which is the same as IL1RL1 [IL1 receptor-like-1].
The ligand has been identified as IL33. For these reasons, the protein is being referred to also as IL33R [IL33 receptor].
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