GDCF |
GDCLPHLKLCKENKDCCSKKCKRRGTNIEKRCR |
PHI-27 |
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[Glioma-derived monocyte chemotactic factor-2] This factor is found in the conditioned medium of human glioma cells (Yoshimura et al, 1989). It has a length of 76 amino acids, including 4 half-cysteines at positions 11, 12, 36, and 52; the amino acid composition of this protein is the same as that of LDCF (lymphocyte-derived chemotactic factor).
GDCF-2 is encoded by the human homolog of the JE gene. GDCF-2 therefore belongs to the family of chemotactic cytokines known as Chemokines. GDCF-2 is chemotactic for human monocytes, but not neutrophils. See also: GDCF
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