GPR159 |
GPR171 |
protein tyrosine phosphatase-zeta |
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[G-protein-coupled receptor 160] In databanks this G-protein-coupled receptor is known also as GPCR1 [G-protein-coupled receptor-1] and GPCR150 [G-protein-coupled receptor-150]. GPR160 is an orphan receptor with unknown ligand(s).
Zhou C et al (2016) have reported that transcription levels of GPR160 in prostate cancer tissue samples and cell lines, such as PC-3, LNCaP, DU145 and 22Rv1 cells, are significantly higher than those in normal prostate tissue and cells. Knock-down of GPR160 leads to upregulastion of genes involved in apoptosis and chemotaxis
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