Genistein

(4',5,7-Trihydroxyisoflavone) This isoflavone compound was detected initially in culture media of Pseudomonas spp in search for quercetin-like flavonoids that, like quercetin, inhibit protein tyrosine kinases. Unlike quercetin, which inhibits tyrosine and serine/threonine kinases, Genistein is a highly specific inhibitor of tyrosine-specific protein kinases in vitro and in vivo with little activity on serine- and threonine-specific protein kinases.

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